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Series: Other Talks

Comparison geometry studies Riemannian manifolds with a given curvature bound. This minicourse is an introduction to volume comparison (as developed by Bishop and Gromov), which is fundamental in understanding manifolds with a lower bound on Ricci curvature. Prerequisites are very modest: we only need basics of Riemannian geometry, and fluency with fundamental groups and metric spaces. In the third (2 hour) lecture I shall prove volume and Laplacian comparison theorems.

Series: Probability Working Seminar

This is a continuation of last week's seminar. The talk is based on a paper by Kuksin, Pyatnickiy, and Shirikyan. In this paper, the convergence to a stationary distribution is established by partial coupling. Here, only finitely many coordinates in the (infinite-dimensional) phase space participate in the coupling while the dynamics takes care of the other coordinates.

Series: SIAM Student Seminar

This talk will follow Peter Lax on the linear algebraic fact of the index of Fredholm operators such as the product formula and stability, all of which are totally elementary.

Series: Stochastics Seminar

Last week we saw combinatorial reconstruction. This time we are going to explain a new approach to Scenery Reconstruction. This new approach could allow us to prove that being able to distinguish sceneries implies reconstructability.

Series: School of Mathematics Colloquium

The study of partition identities has a long history going back to Euler, with applications ranging from Analysis to Number Theory, from Enumerative Combina- torics to Probability. Partition bijections is a combinatorial approach which often gives the shortest and the most elegant proofs of these identities. These bijections are then often used to generalize the identities, find "hidden symmetries", etc. In the talk I will present a modern approach to partition bijections based on the geometry of random partitions and complexity ideas.

Series: ACO Student Seminar

In this talk, I will introduce the class of logconcave and s-concave functions, illustrate their properties, and explain their connections to convex geometry. I will present a simple and unified approach for proving probabilistic inequalities for logconcave and s-concave densities on the real line. Lastly I will use these techniques to prove two important theorems in convex geometry: Grunbaum's theorem, every halfspace cut through the centroid of a convex body contains at least a 1/e volume fraction of the body, and the Milman-Pajor inequality, a convex body in R^n is sandwiched between its inertial ellipsoid and a factor n scaling of it. Joint work with Santosh Vempala.

Series: Research Horizons Seminar

I'll give a brief introduction to the to Quantum Statistical Mechanics in the case of systems of Fermions (e.g. electrons) and try to show that a lot of the mathematical problems can be framed in term of counting (Feynman) graphs or estimating large determinants.

Wednesday, February 25, 2009 - 11:00 ,
Location: Skiles 255 ,
Yuriy Mileyko ,
School of Biology, Georgia Tech ,
Organizer:

The expression dynamics of interacting genes depends on the topology of the regulatory network, the quantitative nature of feedbacks and interactions between DNA, RNA and proteins, and the biochemical state of the intracellular and surrounding environment. In this talk we show that dynamics of a gene regulatory network can also depend sensitively on the copy number of genes and promoters. Genetic regulatory networks include an overrepresentation of subgraphs commonly known as network motifs. We consider positive feedback, bistable feedback, and toggle switch motifs and show that variation in gene copy number can cause a sequence of saddle-node bifurcations in the corresponding differential equations models, which leads to multiple orders of magnitude change in gene expression. A similar analysis of a 3-gene motif with successive inhibition (the ``repressilator'') reveals that changes in gene copy number can also cause a Hopf bifurcation, thus leading to a qualitative switch in system behavior among oscillatory and equilibrium dynamics. Importantly, we show that these bifurcations exist over a wide range of parameter values, thus reinforcing our claim that copy number is a key control parameter in the expression dynamics of regulatory networks.

Series: PDE Seminar

The problem of understanding the parabolic hull of Brownian motion arises in two different fields. In mathematical physics this is the Burgers-Hopf caricature of turbulence (very interesting, even if not entirely turbulent). In statistics, the limit distribution we study was first considered by Chernoff, and forms the cornerstone of a large class of limit theorems that have now come to be called 'cube-root-asymptotics'. It was in the statistical context that the problem was first solved completely in the mid-80s by Groeneboom in a tour de force of hard analysis. We consider another approach to his solution motivated by recent work on stochastic coalescence (especially work of Duchon, Bertoin, and my joint work with Bob Pego). The virtues of this approach are simplicity, generality, and the appearance of a completely unexpected Lax pair. If time permits, I will also indicate some tantalizing links of this approach with random matrices. This work forms part of my student Ravi Srinivasan's dissertation.

Series: CDSNS Colloquium

A plasma is a completed ionized gas. In many applications such as in nuclear fusion or astrophysical phenomena, the plasma has very high temperature and low density, thus collisions can be ignored. The standard kinetic models for a collisionless plasma are the Vlasov- Maxwell and Vlasov-Poisson systems. The Vlasov-Poisson system is also used to model galaxy dynamics, where a star plays the role of a particle. There exists infinitely many equilibria for Vlasov models and their stability is a very important issue in physics. I will describe some of my works on stability and instability of various Vlasov equilibria.