Nonlinear Quantitative Photoacoustic Tomography with Two-photon Absorption

Applied and Computational Mathematics Seminar
Thursday, March 2, 2017 - 14:00
1 hour (actually 50 minutes)
Skiles 006
University of Texas, Austin
Two-photon photoacoustic tomography (TP-PAT) is a non-invasive  optical molecular imaging modality that aims at inferring two-photon absorption property of heterogeneous media from photoacoustic measurements. In this work, we analyze an inverse problem in quantitative TP-PAT where we intend to reconstruct optical coefficients in a semilinear elliptic PDE, the mathematical model for the propagation of near infra-red photons in tissue-like optical media, from the internal absorbed energy data. We derive uniqueness and stability results on the reconstructions of single and multiple coefficients, and perform numerical simulations based on synthetic data to validate the theoretical analysis.