Sequential Minimum Energy Designs: From Nano Experiments to Global Optimization

Series: 
School of Mathematics Colloquium
Thursday, April 14, 2011 - 11:00
1 hour (actually 50 minutes)
Location: 
Skiles 005
,  
ISyE GATech
Motivated by a problem in the synthesis of nanowires, a sequential space filling design, called Sequential Minimum Energy Design (SMED), is proposed for exploring and searching for the optimal conditions in complex black-box functions. The SMED is a novel approach to generate designs that are model independent, can quickly carve out regions with no observable nanostructure morphology, allow for the exploration of complex response surfaces, and can be used for sequential experimentation. It can be viewed as a sequential design procedure for stochastic functions and a global optimization procedure for deterministic functions. The basic idea has been developed into an implementable algorithm, and guidelines for choosing the parameters of SMED have been proposed. Convergence of the algorithm has been established under certain regularity conditions. Performance of the algorithm has been studied using experimental data on nanowire synthesis as well as standard test functions.(Joint work with V. R. Joseph, Georgia Tech and T. Dasgupta, Harvard U.)