Seminars and Colloquia by Series

Optimizing the Combined Treatment of Tumor Growth using Mixed-Effect ODE Modeling

Series
Mathematical Biology Seminar
Time
Wednesday, February 18, 2015 - 11:00 for 1 hour (actually 50 minutes)
Location
Skiles 005
Speaker
Shelby WilsonMorehouse College
An array of powerful mathematical tools can be used to identify the key underlying components and interactions that determine the mechanics of biological systems such as cancer and its interaction with various treatments. In this talk, we describe a mathematical model of tumor growth and the effectiveness of combined chemotherapy and anti-angiogenic therapy (drugs that prevent blood vessel growth). An array of mathematical tools is used in these studies including dynamical systems, linear stability analysis, numerical differential equations, SAEM (Stochastic Approximation of the Expectation Maximization) parameter estimation, and optimal control. We will develop the model using preclinical mouse data and discuss the optimal combination of these cancer treatments. The hope being that accurate modeling/understanding of experimental data will thus help in the development of evidence-based treatment protocols designed to optimize the effectiveness of combined cancer therapies.

Random reflections, symmetrizations, and foldings on the sphere

Series
Math Physics Seminar
Time
Tuesday, February 17, 2015 - 14:05 for 1 hour (actually 50 minutes)
Location
Skiles 005
Speaker
Almut BurchardUniversity of Toronto
Two-point symmetrizations are simple rearrangementsthat have been used to prove isoperimetric inequalitieson the sphere. For each unit vector u, there is atwo-point symmetrization that pushes mass towardsu across the normal hyperplane.How can full rotational symmetry be recovered from partialinformation? It is known that the reflections at d hyperplanes in general position generate a dense subgroup of O(d);in particular, a continuous function that is symmetric under thesereflections must be radial. How many two-point symmetrizationsare needed to verify that a function which increases under thesesymmetrizations is radial? I will show that d+1 such symmetrizationssuffice, and will discuss the ergodicity of the randomwalk generated by the corresponding folding maps on the sphere.(Joint work with G. R. Chambers and Anne Dranovski).

Graph Fourientations and the Tutte Polynomial

Series
Combinatorics Seminar
Time
Monday, February 16, 2015 - 15:05 for 1 hour (actually 50 minutes)
Location
Skiles 005
Speaker
Spencer BackmanUniversity of Rome
A fourientation of a graph is a choice for each edge of whether to orient it in either direction, bidirect it, or leave it unoriented. I will present joint work with Sam Hopkins where we describe classes of fourientations defined by properties of cuts and cycles whose cardinalities are given by generalized Tutte polynomial evaluations of the form: (k+l)^{n-1}(k+m)^g T (\frac{\alpha k + \beta l +m}{k+l}, \frac{\gamma k +l + \delta m}{k+m}) for \alpha,\gamma \in {0,1,2} and \beta, \delta \in {0,1}. We also investigate classes of 4-edge colorings defined via generalized notions of internal and external activity, and we show that their enumerations agree with those of the fourientation classes. We put forth the problem of finding a bijection between fourientations and 4-edge-colorings which respects all of the given classes. Our work unifies and extends earlier results for fourientations due to myself, Gessel and Sagan, and Hopkins and Perkinson, as well as classical results for full orientations due to Stanley, Las Vergnas, Greene and Zaslavsky, Gioan, Bernardi and others.

Analyzing Related Switching Systems: Two Interesting Examples

Series
AMS Club Seminar
Time
Monday, February 16, 2015 - 15:00 for 1 hour (actually 50 minutes)
Location
Skiles 006
Speaker
Dr. Tobias Hurthgraduate of Georgia Tech School of Math

Please Note: Dr. Hurth is a recent graduate of the Georgia Tech School of Mathematics. After his talk, the AMS Graduate Chapter is taking Dr. Hurth to dinner at Gordon Biersch. Graduate students and others interested in speaking to Dr. Hurth are invited to join us. If interested, please RSVP to JD Walsh (in person or at walsh@math.gatech.edu).

Dr. Hurth will talk about two relatively simple, related switching systems: one in 1D, the other in 2D. For both systems, he will sketch how to analyse the density of the associated invariant measure. This is straightforward for the 1D-example, but proves somewhat unexpectedly difficult for the 2D one.

Nonnegative Inverse Eigenvalue and Singular Value Problems

Series
Applied and Computational Mathematics Seminar
Time
Monday, February 16, 2015 - 14:00 for 1 hour (actually 50 minutes)
Location
Skiles 005
Speaker
Prof. Matthew LinNational Chung Cheng University, Georgia Tech

Please Note: Reference[1] Moody T. Chu , Nonnegative Inverse Eigenvalue and Singular Value Problems, SIAM J. Numer. Anal (1992).[2] Wei Ma and Zheng-J. Bai, A regularized directional derivative-based Newton method for inverse singular value problems, Inverse Problems (2012).

Nonnegative inverse eigenvalue and singular value problems have been a research focus for decades. It is true that an inverse problem is trivial if the desired matrix is not restricted to any structure. This talk is to present two numerical procedures, based on a conquering procedure and an alternating projection process, to solve inverse eigenvalue and singular value problems for nonnegative matrices, respectively. In theory, we also discuss the existence of nonnegative matrices subject to prescribed eigenvalues and singular values. Though the focus of this talk is on inverse eigenvalue and singular value problems with nonnegative entries, the entire procedure can be straightforwardly applied to other types of structure with no difficulty.

Equilibrium quasi-periodic configurations in quasi-periodic media

Series
CDSNS Colloquium
Time
Monday, February 16, 2015 - 11:00 for 1 hour (actually 50 minutes)
Location
Skiles 005
Speaker
Lei ZhangGeorgia Institute of Technology
We consider an atomic model of deposition of materials over a quasi-periodic medium. The atoms of the deposited material interact with the medium (a quasi-periodic interaction) and with their nearest neighbors (a harmonic interaction). This is a quasi-periodic version of the well known Frenkel-Kontorova model. We consider the problem of whether there are quasi-periodic equilibria with a frequency that resonates with the frequencies of the medium. We show that there are always perturbative expansions. We also prove a KAM theorem in a-posteriori form. We show that if there is an approximate solution of the equilibrium equation satisfying non-degeneracy conditions, we can adjust one parameter and obtain a true solution which is close to the approximate solution. The proof is based on an iterative method of the KAM type. The iterative method is not based on transformation theory as the most usual KAM theory, but it is based on a novel technique of supplementing the equilibrium equation with another equation that factors the linearization of the equilibrium equilibrium equation.

Introduction to regularity theory of second order Hamilton-Jacobi-Bellman equations.

Series
PDE Working Seminar
Time
Friday, February 13, 2015 - 15:00 for 1 hour (actually 50 minutes)
Location
Skiles 202
Speaker
Andrzej SweichGeorgiaTech
I will give a series of elementary lectures presenting basic regularity theory of second order HJB equations. I will introduce the notion of viscosity solution and I will discuss basic techniques, including probabilistic techniques and representation formulas. Regularity results will be discussed in three cases: degenerate elliptic/parabolic, weakly nondegenerate, and uniformly elliptic/parabolic.

Ultra sub-Gaussian random vectors and Khinchine type inequalities

Series
Stochastics Seminar
Time
Thursday, February 12, 2015 - 15:05 for 1 hour (actually 50 minutes)
Location
Skiles 006
Speaker
Piotr NayarIMA, Minneapolis
We define the class of ultra sub-Gaussian random vectors and derive optimal comparison of even moments of linear combinations of such vectors in the case of the Euclidean norm. In particular, we get optimal constants in the classical Khinchine inequality. This is a joint work with Krzysztof Oleszkiewicz.

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